Protein World Multivitamin Capsules

Multi Vitamin Powder is a product from UK based company Protein World. The product claims that it is a great way to boost your daily intake of vitamins and significantly increases the amount and rate at which the vitamins are absorbed. This review will aim to examine these ingredients to see if it can achieve these claims.


Magnesium Glycinate

Magnesium has been found to be used for 300 biochemical reactions in the body (1). It has been found to maintain muscle function (2), support a healthy immune system (3), keep the heart beat steady (4), and help strengthen bones (5). It has also been found to maintain blood glucose levels (6) and aid in the production of energy and protein.

Ascorbic Acid

Vitamin C is known to be a powerful antioxidant (7). Studies have suggested that it can increase endothelial nitric oxide by protecting it from oxidation and increase synthesis, another function that Vitamin C has suggested includes reducing blood pressure (8), however the only proven function of vitamin C is the prevention of scurvy (9).

Potassium Chloride

Potassium chloride is a form of potassium which has several function such as regulating water balance (10), central nervous system function (11) and helps convert glucose into glycogen which provides energy to the bodies muscles (12).

Vitamin E

Vitamin E has several important functions within the body. Firstly it acts as an antioxidant (13) particularly helping with chronic conditions associated with oxidative stress (14), this is due to its functions of being a chain-breaking antioxidant that prevents the propagation of free radical reactions (15) and also helps protect the body’s cell membranes (16). As well as this it can help maintain healthy skin and eyes (17) and gives a boost to the immune system (18).

Zinc Gluconate

Zinc has been identified as a factor for many enzymes responsible for the synthesis, storage and release of insulin (19), with increases in lean body mass while fat mass either remains stable or decreases, depending on the degree of baseline zinc deficiency (20). With this evidence is has been shown that this ingredient is important for the growth and development of body tissues as well as this a variety of biological processes including wound healing and muscle cramps (21) have been found.

Ferrous Fumarate

Ferrous Fumarate is also known as iron sulphate, common uses for this ingredient are for people with iron deficiency. Iron levels have been found to decline due to exercise (22) with findings showing that it can help with fatigue (23).


Vitamin K is also known as Menaquinone. It is sourced from dark green vegetables and is also derived from the bacteria within the intestines. The benefits of vitamin K include increased bone density (24,25). Cardiovascular health is another benefit of Vitamin K which reduces the stiffness of arteries which can improve circulation (26,27). There are other suggested benefits of vitamin k which include anti cancer properties and improved insulin sensitivity (28,29). Vitamin K has also been found to work well when taken with vitamin D (30,31).  Vitamin K is a fat soluble vitamin and so should be taken with a meal containing fat or a supplement that includes fatty acids.

Manganese Gluconate

Manganese Gluconate is a nutrient which is stored in the liver, kidneys, pancreas and bones. There are several roles that Manganese Gluconate plays within the body, which includes antioxidant (32), the metabolism of carbohydrates (33), helps form and maintain bones (34) and the production of collagen (35). Caution is needed when taking this ingredient however as too much of manganese gluconate can be harmful (36).

Molybdenum Chelate

Molybdenum Chelate is an essential mineral that is normally found in grains and water. This mineral is needed for the function of certain enzymes, however there has been no evidence that an increased intake of Molybdenum Chelate provides any benefits.


Nicotinamide is also known as niacin or vitamin B3 and in an antioxidant. Research studies have shown that niacin supplementation increases growth hormones in response to anaerobic exercise (37) as well as a reduction in fasting triglycerides (38). An increase in fasting insulin has been found due to a decrease in insulin sensitivity (39). Further research is needed for this supplement in order to understand the mechanisms.

Beta Carotene

Beta Carotene is a red / orange pigment that is derived from root vegetables such as carrots. Beta Carotene has been found to convert into Vitamin A (44). Vitamin A is a diverse vitamin that has a wide range of functions. Vision improvement is one positive aspect of vitamin A supplementation (40), another is bone and body growth which can be improved (41). Immune function is boosted by an increase in white blood cells which can destroy harmful bacteria (42). Epithelial cells require Vitamin A in order to function properly, these cells serve as barriers to infection by bacteria and other sources (43). An advantage of Beta Carotene is that the body only converts as much as is required.  

Pyridoxine Hydrochloride

Pyridoxine hydrochloride is a form of Vitamin B6. The active form of vitamin B6 is known as P-L-P (45), which is stimulated by exercise (46). During exercise the body relies on the liver to produce glucose via glycogenolysis, for which vitamin b6 is essential for, and is an integral part of the glycogen phosphorylase enzyme and thus will provide energy to the bodies’ muscles (47).

Thiamin Hydrochloride

Thiamine is also known as vitamin B1 (48) and is essential in carbohydrate metabolism and oxidation (49). The reported effect that have been found includes, a decrease in heart rate, blood glucose and lactate concentrations (50).


Riboflavin is a nutrient that has been found to help in fat metabolism via the electron-transport chain (51) and an antioxidant (52). It is also one of many nutrients that helps in the production of red blood cells. Levels of riboflavin has been found to diminish during exhaustive exercise (53).


Cholecalciferol is a form of Vitamin D and helps with the absorption of calcium in the stomach (60). Calcium is a vital part of dietary consumption in order to aid growth and maintenance of bones (54). Other important benefits of calcium include helping blood clotting (55), heart contractions (56), lungs (57) and muscles to function properly (58), this is due to calcium binding with phosphate to create calcium phosphate (59).


Cyanocobalamin is also known as Vitamin B12. Research studies on vitamin B12 have found that it is required for red blood cell production (61), protein synthesis and the repair and maintenance of tissue cells (62).

Chromium Picolinate

Chromium picolinate is stored in the liver. It has been found to increase the absorption of vitamin C and Niacin (63, 64) as well as enhancing the role of insulin which is responsible for the metabolism of fats, carbohydrates and protein (65).

Folic Acid

Folic acid is also known as folate is a water soluble mineral that, along with other nutrients is necessary for red blood cell production (66). It can also help regulate nitric oxide levels in the blood (67).

Potassium Iodide

Potassium iodide is known as a thyroid mineral (68) as it keeps iodine levels regulated in the thyroid (69). To date there is no research examining the effects of potassium iodide on athletic performance.

Sodium Selenite

Sodium Selenite or Selenium as it is also known as is a chemical element that is best known for its antioxidant properties as it is the component of the antioxidant enzymes glutathione peroxidase and thioredoxin reductase (70). Selenium also plays a role in the functioning of the thyroid gland and in every cell that uses thyroid hormone (71). The thyroid gland controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones.


Biotin can also be know as vitamin B7 or Vitamin H. it has been found that it can contribute to metabolism and cell development (72) as well as providing energy during exercise (73).


With the vast amounts of ingredients within this supplement it can be easy to assume that it can live up to the claims that it can boost your daily intake of nutrients and minerals. However some ingredients within this supplement have no evidence that they can have any benefit. This product can be consumed at any point of the day. This product has no banned substances when referring to the WADA prohibited list when observing the label / ingredients posted on the website.

*NOTE – This product has not been tested in a laboratory and may contain other substances that may not appear on the label


1 – Ryan, M. F. (1991). The role of magnesium in clinical biochemistry: an overview.Annals of Clinical Biochemistry: An international journal of biochemistry in medicine, 28(1), 19-26.

2 – Dørup, I., Skajaa, K., Clausen, T., & Kjeldsen, K. (1988). Reduced concentrations of potassium, magnesium, and sodium-potassium pumps in human skeletal muscle during treatment with diuretics. British medical journal (Clinical research ed.), 296(6620), 455.

3 – Tam, M., Gomez, S., Gonzalez-Gross, M., & Marcos, A. (2003). Possible roles of magnesium on the immune system. European journal of clinical nutrition,57(10), 1193-1197.

4 – White, R. E., & Hartzell, H. C. (1989). Magnesium ions in cardiac function: regulator of ion channels and second messengers. Biochemical pharmacology,38(6), 859-867.

5 – Okuma, T. (2001). Magnesium and bone strength. Nutrition, 17(7), 679-680.

6 – Paolisso, G., Scheen, A., d’Onofrio, F., & Lefèbvre, P. (1990). Magnesium and glucose homeostasis. Diabetologia, 33(9), 511-514.

7 – Kalt, W., Forney, C. F., Martin, A., & Prior, R. L. (1999). Antioxidant capacity, vitamin C, phenolics, and anthocyanins after fresh storage of small fruits.Journal of Agricultural and Food Chemistry, 47(11), 4638-4644.

8 – Huang, A., Vita, J. A., Venema, R. C., & Keaney, J. F. (2000). Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin. Journal of biological chemistry, 275(23), 17399-17406.

9 – Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., … & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition, 22(1), 18-35.

10 – Lemann Jr, J., Pleuss, J. A., Gray, R. W., & Hoffmann, R. G. (1991). Potassium administration increases and potassium deprivation reduces urinary calcium excretion in healthy adults. Kidney Int, 39(5), 973-983.

11 – Goto, A. T. S. U. O., Tobian, L., & Iwai, J. (1981). Potassium feeding reduces hyperactive central nervous system pressor responses in Dahl salt-sensitive rats. Hypertension, 3(3 Pt 2), I128.

12 – Brady, R. O., Mamoon, A. M., & Stadtman, E. R. (1956). The effects of citrate and coenzyme A on fatty acid metabolism. Journal of Biological Chemistry,222(2), 795-802.

13 – Burton, G. W., & Traber, M. G. (1990). Vitamin E: antioxidant activity, biokinetics, and bioavailability. Annual review of nutrition, 10(1), 357-382.

14 – Brigelius-Flohe, R., & Traber, M. G. (1999). Vitamin E: function and metabolism. The FASEB Journal, 13(10), 1145-1155.

15 – Tappel, A. L. (1962). Vitamin E as the biological lipid antioxidant. Vitamins & Hormones, 20, 493-510.

16 –  Packer, L. (1991). Protective role of vitamin E in biological systems. The American journal of clinical nutrition, 53(4), 1050S-1055S.

17  – Bartlett, H. E., & Eperjesi, F. (2008). A randomised controlled trial investigating the effect of lutein and antioxidant dietary supplementation on visual function in healthy eyes. Clinical Nutrition, 27(2), 218-227.

18 – Meydani, S. N., Meydani, M., Blumberg, J. B., Leka, L. S., Siber, G., Loszewski, R., … & Stollar, B. D. (1997). Vitamin E supplementation and in vivo immune response in healthy elderly subjects: a randomized controlled trial.Jama, 277(17), 1380-1386.

19 – Hashemipour, M., Kelishadi, R., Shapouri, J., Sarrafzadegan, N., Amini, M., Tavakoli, N., … & Poursafa, P. (2009). Effect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese children. Hormones (Athens), 8(4), 279-285.

20 – Prasad, A. S. (1991). Discovery of human zinc deficiency and studies in an experimental human model. The American journal of clinical nutrition, 53(2), 403-412.

21 – Kugelmas, M. (2000). Preliminary observation: oral zinc sulfate replacement is effective in treating muscle cramps in cirrhotic patients. Journal of the American College of Nutrition, 19(1), 13-15.

22 – Weaver, C. M., & Rajaram, S. (1992). Exercise and iron status. The Journal of nutrition, 122(3 Suppl), 782-787.

23 – Brutsaert, T. D., Hernandez-Cordero, S., Rivera, J., Viola, T., Hughes, G., & Haas, J. D. (2003). Iron supplementation improves progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women. The American journal of clinical nutrition, 77(2), 441-448.

24 – Booth, S. L., Dallal, G., Shea, M. K., Gundberg, C., Peterson, J. W., & Dawson-Hughes, B. (2008). Effect of vitamin K supplementation on bone loss in elderly men and women. The Journal of Clinical Endocrinology & Metabolism, 93(4), 1217-1223.

25 – Knapen, M. H. J., Drummen, N. E., Smit, E., Vermeer, C., & Theuwissen, E. (2013). Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International,24(9), 2499-2507.

26 – Kuwabara, K., Pinsky, D. J., Schmidt, A. M., Benedict, B., Brett, B., Ogawa, S., … & Wang, F. (1995). Calreticulin, an antithrombotic agent which binds to vitamin K-dependent coagulation factors, stimulates endothelial nitric oxide production, and limits thrombosis in canine coronary arteries. Journal of Biological Chemistry, 270(14), 8179-8187.

27 – Shearer, M. J. (2000). Role of vitamin K and Gla proteins in the pathophysiology of osteoporosis and vascular calcification. Current Opinion in Clinical Nutrition & Metabolic Care, 3(6), 433-438.

28 – Ishizuka, M., Kubota, K., Shimoda, M., Kita, J., Kato, M., Park, K. H., & Shiraki, T. (2012). Effect of menatetrenone, a vitamin k2 analog, on recurrence of hepatocellular carcinoma after surgical resection: a prospective randomized controlled trial. Anticancer research, 32(12), 5415-5420.

29 – Sakamoto, N., Nishiike, T., Iguchi, H., & Sakamoto, K. (2000). Possible effects of one week vitamin K (menaquinone-4) tablets intake on glucose tolerance in healthy young male volunteers with different descarboxy prothrombin levels. Clinical Nutrition, 19(4), 259-263.

30 – Iwamoto, I., Kosha, S., Noguchi, S. I., Murakami, M., Fujino, T., Douchi, T., & Nagata, Y. (1999). A longitudinal study of the effect of vitamin K 2 on bone mineral density in postmenopausal women a comparative study with vitamin D 3 and estrogen–progestin therapy. Maturitas, 31(2), 161-164.

31 – Ushiroyama, T., Ikeda, A., & Ueki, M. (2002). Effect of continuous combined therapy with vitamin K 2 and vitamin D 3 on bone mineral density and coagulo fibrinolysis function in postmenopausal women. Maturitas, 41(3), 211-221.

32 – Cheng, T. Y., Zhu, Z., Masuda, S., & Morcos, N. C. (2001). Effects of multinutrient supplementation on antioxidant defense systems in healthy human beings. The Journal of nutritional biochemistry, 12(7), 388-395.

33 – Webley, D. M., Duff, R. B., & Anderson, G. (1962). The metabolism of iron-, zinc-and manganese-deficient Nocardia opaca. Microbiology, 29(1), 179-187.

34 – Krumhar, Kim C., and Holly A. Johnson. “Composition for promoting healthy bone structure.” U.S. Patent 7,029,703, issued April 18, 2006.

35 – Tenaud, I., Sainte-Marie, I., Jumbou, O., Litoux, P., & Dreno, B. (1999). In vitro modulation of keratinocyte wound healing integrins by zinc, copper and manganese. British Journal of Dermatology, 140, 26-34.

36 – Schaefer, S., Lange, R. A., Kulkarni, P. V., Katz, J., Parkey, R. W., Willerson, J. T., & Peshock, R. M. (1989). In vivo nuclear magnetic resonance imaging of myocardial perfusion using the paramagnetic contrast agent manganese gluconate. Journal of the American College of Cardiology, 14(2), 472-480.

37 – Stokes, K. A., Tyler, C., & Gilbert, K. L. (2008). The growth hormone response to repeated bouts of sprint exercise with and without suppression of lipolysis in men. Journal of Applied Physiology, 104(3), 724-728.

38  – Plaisance, E. P., Mestek, M. L., Mahurin, A. J., Taylor, J. K., Moncada-Jimenez, J., & Grandjean, P. W. (2008). Postprandial triglyceride responses to aerobic exercise and extended-release niacin. The American journal of clinical nutrition, 88(1), 30-37.

39 – Vega, G. L., Cater, N. B., Meguro, S., & Grundy, S. M. (2005). Influence of extended-release nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemia. The American journal of cardiology, 95(11), 1309-1313.

40 – Rando, R. R. (1990). The chemistry of vitamin A and vision. Angewandte Chemie International Edition in English, 29(5), 461-480.

41 – Mellanby, E. (1947). Vitamin A and bone growth: the reversibility of vitamin A‐deficiency changes. The Journal of physiology, 105(4), 382-399.

42 – Stephensen, C. B. (2001). Vitamin A, infection, and immune function*. Annual review of nutrition, 21(1), 167-192.

43 – Batourina, E., Choi, C., Paragas, N., Bello, N., Hensle, T., Costantini, F. D., … & Mendelsohn, C. L. (2002). Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret. Nature genetics, 32(1), 109-115.

44 – Olson, J. A. (1989). Provitamin A function of carotenoids: the conversion of beta-carotene into vitamin A. The Journal of nutrition, 119(1), 105-108.

45 – Ubbink, J. B., Vermaak, W. J., van der Merwe, A., & Becker, P. J. (1993). Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. The American journal of clinical nutrition, 57(1), 47-53.

46 – Manore, M. M. (2000). Effect of physical activity on thiamine, riboflavin, and vitamin B-6 requirements. The American journal of clinical nutrition, 72(2), 598s-606s.

47 – Manore, M. N., Leklem, J. E., & Walter, M. C. (1987). Vitamin B-6 metabolism as affected by exercise in trained and untrained women fed diets differing in carbohydrate and vitamin B-6 content. The American journal of clinical nutrition,46(6), 995-1004.

48 – Webster, M. J., Scheett, T. P., Doyle, M. R., & Branz, M. (1997). The effect of a thiamin derivative on exercise performance. European journal of applied physiology and occupational physiology, 75(6), 520-524.

49 – Davis, R. E., & Icke, G. C. (1983). Clinical chemistry of thiamin. Advances in clinical chemistry, 23, 93.

50 – Knippel, M., Mauri, L., Belluschi, R., Bana, G., Galli, C., Pusterla, G. L., . & Troina, E. (1986). The action of thiamin on the production of lactic acid in cyclists. Med Sport, 39(1), 11.

51 – Powers, H. J. (2003). Riboflavin (vitamin B-2) and health. The American journal of clinical nutrition, 77(6), 1352-1360.

52 – Sugiyama, M. (1992). Role of physiological antioxidants in chromium (VI)-induced cellular injury. Free Radical Biology and Medicine, 12(5), 397-407.

53 – Belko, A. Z., Obarzanek, E., Roach, R., Rotter, M., Urban, G., Weinberg, S., & Roe, D. A. (1984). Effects of aerobic exercise and weight loss on riboflavin requirements of moderately obese, marginally deficient young women. The American journal of clinical nutrition, 40(3), 553-561.

54 – Harada, S. I., & Rodan, G. A. (2003). Control of osteoblast function and regulation of bone mass. Nature, 423(6937), 349-355.

55 – Bogdanova, A., Makhro, A., Wang, J., Lipp, P., & Kaestner, L. (2013). Calcium in Red Blood Cells—A Perilous Balance. International journal of molecular sciences, 14(5), 9848-9872.

56 – Dhalla, N. S., Pierce, G. N., Panagia, V., Singal, P. K., & Beamish, R. E. (1982). Calcium movements in relation to heart function. Basic research in cardiology, 77(2), 117-139.

57 – Hawgood, S., Benson, B. J., & Hamilton Jr, R. L. (1985). Effects of a surfactant-associated protein and calcium ions on the structure and surface activity of lung surfactant lipids. Biochemistry, 24(1), 184-190.

58 – Berchtold, M. W., Brinkmeier, H., & Müntener, M. (2000). Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease.Physiological reviews, 80(3), 1215-1265.

59 – Shanahan, C. M., Crouthamel, M. H., Kapustin, A., & Giachelli, C. M. (2011). Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circulation research, 109(6), 697-711.

60 – Spencer, R., Charman, M., Wilson, P., & Lawson, E. (1976). Vitamin D-stimulated intestinal calcium absorption may not involve calcium-binding protein directly.

61 – d’Onofrio, G., Chirillo, R., Zini, G., Caenaro, G., Tommasi, M., & Micciulli, G. (1995). Simultaneous measurement of reticulocyte and red blood cell indices in healthy subjects and patients with microcytic and macrocytic anemia. Blood,85(3), 818-823.

62 – Fenech, M. (2001). The role of folic acid and vitamin B12 in genomic stability of human cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 475(1), 57-67.

63- Offenbacher, E. G. (1994). Promotion of chromium absorption by ascorbic acid.Trace elements in medicine, 11(4), 178-181.

64 – Bagchi, D., Stohs, S. J., Downs, B. W., Bagchi, M., & Preuss, H. G. (2002). Cytotoxicity and oxidative mechanisms of different forms of chromium.Toxicology, 180(1), 5-22.

65 – Anderson, R. A., Polansky, M. M., Bryden, N. A., Roginski, E. E., Mertz, W., & Glinsmann, W. (1983). Chromium supplementation of human subjects: effects on glucose, insulin, and lipid variables. Metabolism, 32(9), 894-899.

66  – Choumenkovitch, S. F., Jacques, P. F., Nadeau, M. R., Wilson, P. W., Rosenberg, I. H., & Selhub, J. (2001). Folic acid fortification increases red blood cell folate concentrations in the Framingham study. The Journal of nutrition,131(12), 3277-3280.

67 – Stroes, E. S. G., Van Faassen, E. E., Yo, M., Martasek, P., Boer, P., Govers, R., & Rabelink, T. J. (2000). Folic acid reverts dysfunction of endothelial nitric oxide synthase. Circulation research, 86(11), 1129-1134.

68 – Marine, D. (1935). The physiology and principal interrelations of the thyroid.Journal of the American Medical Association, 104(25), 2250-2255.

69 – Cavalieri, R. R. (1997). Iodine metabolism and thyroid physiology: current concepts. Thyroid, 7(2), 177-181.

70 – Battin, E. E., Perron, N. R., & Brumaghim, J. L. (2006). The central role of metal coordination in selenium antioxidant activity. Inorganic chemistry, 45(2), 499-501.

71 – Kohrle, J., Jakob, F., Contempre, B., & Dumont, J. E. (2005). Selenium, the thyroid, and the endocrine system. Endocrine reviews, 26(7), 944-984.

72 – Barone, S. (1988). Vitamins and athletes. In Drugs, Athletes, and Physical Performance (pp. 1-9). Springer US.

73 – Lukaski HC. Vitamin and mineral status: effects on physical performance. Nutrition. 2004;20:632-44

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Price  £9.99