Protein World Premium CLA Review

CLA Powder is a product from UK based company Protein World. The supplement is a naturally occurring fatty acid and this review is will aim to understand what this supplement can achieve.

CLA

Conjugated Linoleic Acid (CLA) has been shown to have weight loss properties (1); there are several reasons for this which includes an increase in energy metabolism (2), insulin resistance (3), stimulation of lipolysis, which is due to an impaired signalling which reduces triglyceride synthesis and releases free fatty acid which normally occurs when energy demand rises (4). Other mechanisms include a suppression of appetite (5), induced adipocyte apoptosis which decreases body fat mass and increased energy expenditure (6).

Gelatine (capsule)

Gelatine is a protein which is made from amino acids glycine and proline. The suggested benefits of gelatin have been to boost metabolism and increase satiety, however there is insufficient evidence to reinforce these claims.

Glycerine

Glycerin is a thick colourless, odourless liquid which has been suggested to be a hyper hydrating agent (7). The main reason for this is that it can increase blood osmolality which augments the retention of water (8). It has been suggested to lower heart rate and prolonged exercise (9), however research is still sparse on this ingredient further studies are needed in order to fully understand the capabilities of glycerin.

Purified Water

Water is water and can hydrate.

This supplement can help with several functions within the body. The advantage of this supplement is that it consists of only one ingredient which means there are no other ingredients that can interfere or compete. It is recommended that this product be taken pre workout. This product has no banned substances when referring to the WADA prohibited list when observing the label / ingredients posted on the website.

*NOTE – This product has not been tested in a laboratory and may contain other substances that may not appear on the label

1 – Blankson, H., Stakkestad, J. A., Fagertun, H., Thom, E., Wadstein, J., & Gudmundsen, O. (2000). Conjugated linoleic acid reduces body fat mass in overweight and obese humans. The Journal of nutrition, 130(12), 2943-2948.

2 – House, R. L., Cassady, J. P., Eisen, E. J., McIntosh, M. K., & Odle, J. (2005). Conjugated linoleic acid evokes de‐lipidation through the regulation of genes controlling lipid metabolism in adipose and liver tissue. obesity reviews, 6(3), 247-258.

3 – Chung, S., Brown, J. M., Provo, J. N., Hopkins, R., & McIntosh, M. K. (2005). Conjugated linoleic acid promotes human adipocyte insulin resistance through NFκB-dependent cytokine production. Journal of Biological Chemistry, 280(46), 38445-38456.

4 – Evans, M., Lin, X., Odle, J., & McIntosh, M. (2002). Trans-10, cis-12 conjugated linoleic acid increases fatty acid oxidation in 3T3-L1 preadipocytes. The Journal of nutrition, 132(3), 450-455.

5 – Medina, E. A., Horn, W. F., Keim, N. L., Havel, P. J., Benito, P., Kelley, D. S., … & Erickson, K. L. (2000). Conjugated linoleic acid supplementation in humans: effects on circulating leptin concentrations and appetite. Lipids, 35(7), 783-788.

6 – Zambell, K. L., Keim, N. L., Van Loan, M. D., Gale, B., Benito, P., Kelley, D. S., & Nelson, G. J. (2000). Conjugated linoleic acid supplementation in humans: effects on body composition and energy expenditure. Lipids, 35(7), 777-782.

7 –  WAGNER, D. (1999). Hyperhydrating with glycerol: implications for athletic performance. Journal of the American Dietetic Association, 99(2), 207-212.

8 – Robergs, R. A., & Griffin, S. E. (1998). Glycerol. Sports Medicine, 26(3), 145-167.

9 – Montner, P., Stark, D. M., Riedesel, M. L., Murata, G., Robergs, R., Timms, M., & Chick, T. W. (1996). Pre-exercise glycerol hydration improves cycling endurance time. International Journal of Sports Medicine, 17(01), 27-33.