Peeroton Vital Fabric Review

Vital Fabric is a supplement from Austrian based company Peeroton. Peeroton claims that this supplement strengthens bones, cartilage, tendons and muscles after exercise as well as accelerating regeneration after injury. This review will aim to assess the ingredients in this supplement to understand if and how it could achieve this.

Ingredients

Calcium carbonate

Calcium carbonate is used as an acidity regulator, anticaking agent, stabiliser or colour.

Disodium phosphate

Disodium phosphate is an inorganic compound which is used as a food additive that helps keep water based and oil based products mixed together that would normally separate.

Microcrystalline cellulose

Micro Crystalline Cellulose is a non-active ingredient which is made up of refined wood pulp. This substance doesn’t degrade during digestion and is preferable in tablets due to it being able to form hard but dissolve quickly.

Hydroxypropyl methylcellulose

Hydroxypropyl methylcellulose does not have any nutritional benefit as its main use is to protect nutrients from the bodies stomach acid.

Chondroitin sulfate from shark cartilage

Chondroitin sulfate is a chemical that is found in cartilage. It has been found that this chemical can help with individuals with arthritis by reducing pain and inflammation by preventing enzymes that break down cartilage (1).

 

Ferrous fumarate

Ferrous sulphate is also known as iron sulphate, common uses for this ingredient are for people with iron deficiency. Iron levels have been found to decline due to exercise (2) with findings showing that it can help with fatigue (3).

Cupric gluconate

Cupric gluconate or copper gluconate as it is also called, has been suggested to contribute to the formation of red blood cells, healthy contribution to the growth and development of bones and organs as well as a participation in cholesterol and glucose metabolism (4). However although there has been evidence for this it is debated and others have found no change when administering copper gluconate compared to a placebo in healthy individuals (5, 6).

Magnesium stearate

Magnesium stearate does not induce any nutritional benefits. The main reason for this substance being in the supplement is that it is a lubricant for the machinery that manufactures the product.

Maltodextrin

Maltodextrin is a polysaccharide which is a complex carbohydrate. This ingredient is water soluble and unlike other carbohydrates, is easily digestible (7) and can give a quick release of energy without any spikes of glycaemia (8).

Vitamin A acetate

Vitamin A is a diverse vitamin that has a wide range of functions. Vision improvement is one positive aspect of vitamin A supplementation (9), Another is bone and body growth which can be improved (10). Immune function is boosted by an increase of white blood cells which can destroy harmful bacteria (11). Epithelial cells require Vitamin A in order to function properly, these cells serve as barriers to infection by bacteria and other sources (12).

Glucosamine hydrochloride crustaceans

Glucosamine hydrochloride originates from seashells. The main function of this ingredient is that it aids in populations with arthritis and joints problems (13). This is due to this chemical making a cushion effect around the joint which protects it. There is insufficient evidence for this however and more studies are needed in order to fully determine its effects.

Zinc gluconate

Zinc has been identified as a factor for many enzymes responsible for the synthesis, storage and release of insulin (14), with increases in lean body mass while fat mass either remains stable or decreases, depending on the degree of baseline zinc deficiency (15). With this evidence is has been shown that this ingredient is important for the growth and development of body tissues as well as this a variety of biological processes including wound healing and muscle cramps (16) have been found.

Titanium dioxide

Titanium dioxide does not provide any nutritional benefits and is used as a whitening agent and a thickener in supplements.

Calcium pantothenate

Calcium D-pantothenate (pantothenic acid) is otherwise known as vitamin B5 and is water soluble. This ingredient helps keep a healthy digestive tract (17) and uses vitamin B2 (18). Pantothenic acid has pantethine which has been found to lower cholesterol (19).

Vitamin B6

The active form of vitamin B6 is known as P-L-P (20), which is stimulated by exercise (21). During exercise the body relies on the liver to produce glucose via glycogenolysis, for which vitamin b6 is essential for, and is an integral part of the glycogen phosphorylase enzyme and thus will provide energy to the bodies’ muscles (22).

Vitamin B2

Riboflavin is a nutrient that has been found to help in fat metabolism via the electron-transport chain (23) and an antioxidant (24). It is also one of many nutrients that helps in the production of red blood cells. Levels of riboflavin has been found to diminish during exhaustive exercise (25).

Sucralose

Sucralose is a sweetener that is calorie free. This ingredient is used in many products and is used to make the product taste sweeter and does not have any nutritional benefit.

Acacia

Acacia is a water soluble dietary fibre, which have been reported to reduce total cholesterol; however there seems to be insufficient evidence to confirm this theory. (26)

Corn starch

Corn starch has no nutritional benefits as its function in supplements is to protect vitamins on their passage through the bodies stomach.

Folic acid

Folic acid is also known as folate is a water soluble mineral that, along with other nutrients is necessary for red blood cell production (27). It can also help regulate nitric oxide levels in the blood (28).

Biotin

Biotin can also be know as vitamin B7 or Vitamin H. it has been found that it can contribute to metabolism and cell development (29) as well as providing energy during exercise (30).

Cholecalciferol

Cholecalciferol is a form of Vitamin D and helps in the absorption of calcium in the stomach (37). Calcium is a vital part of dietary consumption in order to aid growth and maintenance of bones (31). Other important benefits of calcium include helping blood clotting (32), heart contractions (33), lungs (34) and muscles to function properly (35), this is due to calcium binding with phosphate to create calcium phosphate (36).

Summary

Research suggests that among the large number of ingredients within this supplement, many do back up the product’s claims of strengthening bones, cartilage and tendons. There is also some evidence to suggest that this supplement can aid recovery as well. This supplement should be consumed post-workout. This supplement has no banned substances when referring to the WADA prohibited list when observing the label/ingredients posted on the website.

*NOTE – This product has not been tested in a laboratory and may contain other substances that may not appear on the label

References

1 – Sawitzke, A. D., Shi, H., Finco, M. F., Dunlop, D. D., Bingham, C. O., Harris, C. L., … & Clegg, D. O. (2008). The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial. Arthritis & Rheumatism,58(10), 3183-3191.
2 – Weaver, C. M., & Rajaram, S. (1992). Exercise and iron status. The Journal of nutrition, 122(3 Suppl), 782-787.

3 – Brutsaert, T. D., Hernandez-Cordero, S., Rivera, J., Viola, T., Hughes, G., & Haas, J. D. (2003). Iron supplementation improves progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women. The American journal of clinical nutrition, 77(2), 441-448.

4 – Amestica, L., & SA, C. A. COPPER IN HUMANS

5 – Baker, A., Turley, E., Bonham, M. P., O’Connor, J. M., Strain, J. J., Flynn, A., & Cashman, K. D. (1999). No effect of copper supplementation on biochemical markers of bone metabolism in healthy adults. British Journal of Nutrition,82(04), 283-290..

6 – Pratt, W. B., Omdahl, J. L., & Sorenson, J. R. (1985). Lack of effects of copper gluconate supplementation. The American journal of clinical nutrition, 42(4), 681-682.

7 – Haralampu, S. G. (2000). Resistant starch—a review of the physical properties and biological impact of RS< sub> 3</sub>. Carbohydrate polymers, 41(3), 285-292.

8 – Roberts, M., Lockwood, C., Dalbo, V. J., Tucker, P., Frye, A., Polk, R., … & Kerksick, C. (2009). Ingestion of a high molecular weight modified waxy maize starch alters metabolic responses to prolonged exercise in trained cyclists. In FASEB abstract.

9 – Rando, R. R. (1990). The chemistry of vitamin A and vision. Angewandte Chemie International Edition in English, 29(5), 461-480.
10 – Mellanby, E. (1947). Vitamin A and bone growth: the reversibility of vitamin A‐deficiency changes. The Journal of physiology, 105(4), 382-399.
11 – Stephensen, C. B. (2001). Vitamin A, infection, and immune function*. Annual review of nutrition, 21(1), 167-192.
12 – Batourina, E., Choi, C., Paragas, N., Bello, N., Hensle, T., Costantini, F. D., … & Mendelsohn, C. L. (2002). Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret. Nature genetics, 32(1), 109-115.
13 – Houpt, J. B., McMillan, R., Wein, C., & Paget-Dellio, S. D. (1999). Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee.The Journal of rheumatology, 26(11), 2423-2430.
14 – Hashemipour, M., Kelishadi, R., Shapouri, J., Sarrafzadegan, N., Amini, M., Tavakoli, N., … & Poursafa, P. (2009). Effect of zinc supplementation on insulin resistance and components of the metabolic syndrome in prepubertal obese children. Hormones (Athens), 8(4), 279-285.

15 – Prasad, A. S. (1991). Discovery of human zinc deficiency and studies in an experimental human model. The American journal of clinical nutrition, 53(2), 403-412.

16 – Kugelmas, M. (2000). Preliminary observation: oral zinc sulfate replacement is effective in treating muscle cramps in cirrhotic patients. Journal of the American College of Nutrition, 19(1), 13-15.
17 – Millman, P. L. (1989). U.S. Patent No. 4,871,550. Washington, DC: U.S. Patent and Trademark Office.

18 – Blake, C. J. (2007). Analytical procedures for water-soluble vitamins in foods and dietary supplements: a review. Analytical and bioanalytical chemistry,389(1), 63-76.

19 – Hendler SS, Rorvik DR, eds. PDR for Nutritional Supplements. Montvale: Medical Economics Company, Inc; 2001

20 – Ubbink, J. B., Vermaak, W. J., van der Merwe, A., & Becker, P. J. (1993). Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. The American journal of clinical nutrition, 57(1), 47-53.

21 – Manore, M. M. (2000). Effect of physical activity on thiamine, riboflavin, and vitamin B-6 requirements. The American journal of clinical nutrition, 72(2), 598s-606s.

22 – Manore, M. N., Leklem, J. E., & Walter, M. C. (1987). Vitamin B-6 metabolism as affected by exercise in trained and untrained women fed diets differing in carbohydrate and vitamin B-6 content. The American journal of clinical nutrition,46(6), 995-1004.

23 – Powers, H. J. (2003). Riboflavin (vitamin B-2) and health. The American journal of clinical nutrition, 77(6), 1352-1360.

24 – Sugiyama, M. (1992). Role of physiological antioxidants in chromium (VI)-induced cellular injury. Free Radical Biology and Medicine, 12(5), 397-407.

25 – Belko, A. Z., Obarzanek, E., Roach, R., Rotter, M., Urban, G., Weinberg, S., & Roe, D. A. (1984). Effects of aerobic exercise and weight loss on riboflavin requirements of moderately obese, marginally deficient young women. The American journal of clinical nutrition, 40(3), 553-561.

26 – Jensen, C. D., Spiller, G. A., Gates, J. E., Miller, A. F., & Whittam, J. H. (1993). The effect of acacia gum and a water-soluble dietary fiber mixture on blood lipids in humans. Journal of the American College of Nutrition, 12(2), 147-154.

27 – Choumenkovitch, S. F., Jacques, P. F., Nadeau, M. R., Wilson, P. W., Rosenberg, I. H., & Selhub, J. (2001). Folic acid fortification increases red blood cell folate concentrations in the Framingham study. The Journal of nutrition,131(12), 3277-3280.

28 – Stroes, E. S. G., Van Faassen, E. E., Yo, M., Martasek, P., Boer, P., Govers, R., & Rabelink, T. J. (2000). Folic acid reverts dysfunction of endothelial nitric oxide synthase. Circulation research, 86(11), 1129-1134.

29 – Barone, S. (1988). Vitamins and athletes. In Drugs, Athletes, and Physical Performance (pp. 1-9). Springer US.

30 – Lukaski HC. Vitamin and mineral status: effects on physical performance. Nutrition. 2004;20:632-44

31 – Harada, S. I., & Rodan, G. A. (2003). Control of osteoblast function and regulation of bone mass. Nature, 423(6937), 349-355.

32 – Bogdanova, A., Makhro, A., Wang, J., Lipp, P., & Kaestner, L. (2013). Calcium in Red Blood Cells—A Perilous Balance. International journal of molecular sciences, 14(5), 9848-9872.

33 – Dhalla, N. S., Pierce, G. N., Panagia, V., Singal, P. K., & Beamish, R. E. (1982). Calcium movements in relation to heart function. Basic research in cardiology, 77(2), 117-139.

34 – Hawgood, S., Benson, B. J., & Hamilton Jr, R. L. (1985). Effects of a surfactant-associated protein and calcium ions on the structure and surface activity of lung surfactant lipids. Biochemistry, 24(1), 184-190.

35 – Berchtold, M. W., Brinkmeier, H., & Müntener, M. (2000). Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease.Physiological reviews, 80(3), 1215-1265.

36 – Shanahan, C. M., Crouthamel, M. H., Kapustin, A., & Giachelli, C. M. (2011). Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circulation research, 109(6), 697-711.
37 – Spencer, R., Charman, M., Wilson, P., & Lawson, E. (1976). Vitamin D-stimulated intestinal calcium absorption may not involve calcium-binding protein directly.

Use for  Recovery
Website  peeroton.com
Price  €28.90